He also finished the season five goals clear of the next leading scorer, Cristiano Ronaldo of Juventus.
Brazil midfielder Casemiro stretched Real's advantage right before halftime with a gut-busting run to meet a cross from compatriot Vinicius, but Levante hit back shortly after the interval through former Madrid forward Borja Mayoral.
Defender Miguel Britos was sent off for head-butting an opponent as Napoli lost 3-1 at champions Juventus on Saturday, all but ending their hopes of Champions League football next season.
The Juventus striker has rarely managed to demonstrate his real worth on the greatest stages the sport offers.
Barcelona crashed out of the Champions League following a 3-0 defeat at Bayern Munich on Wednesday, failing to make it past the group stage of the competition for the first time since the 2000-01 season.
Images from the football matches played across Europe on Sunday.
Juventus rehire Allegri.
Chelsea, Bayern Munich, Real Madrid and Juventus consolidated their top-flight leads at the weekend while Paris St Germain proved too strong for Ligue 1 leaders Olympique Marseille.
News of all that's transpired on and off the football field
Italy will even be back to four teams in the Champions League group stage this season -- although that is thanks to a controversial re-formulation of the competition by UEFA rather than a significant improvement in performances by Serie A clubs.
AC Milan ruthlessly extinguished any remote prospect of a footballing fairytale as they hammered third-tier Alessandria 5-0 in the second leg of their Italian Cup semi-final on Tuesday.
Photos from the UEFA Champions League matches played across Europe on Wednesday
They say never go back, but United fans had been longing for Ronaldo to rejoin their side for many years, more in forlorn hope than anything else.
IMAGES from Serie A matches played in Italy on Wednesday.
A summary of Saturday's action in Ligue 1, La Liga and Serie A.
Blames mid-week Champions League win against Juve for 'mental pressure'
All the latest football news from around Europe.
News of all that's transpired on and off the football field.
Images from football matches played in Europe on Sunday.
Real, Barca and Juve stand firm on Super League
Mateo Kovacic's late strike avoided embarrassment for Real Madrid as the European champions surrendered a two-goal lead before drawing 3-3 with Legia Warsaw in an enthralling Champions League game played amid an empty stadium on Wednesday.
News of all that's transpired on and off the football field
Check out the top footballers of the weekend...
Sevilla missed a chance to get their La Liga campaign up and running when the Europa League holders surrendered the lead and were held to a 1-1 draw at Levante on Friday.
New strikers Carlos Bacca and Luiz Adriano bagged their maiden Serie A goals to give AC Milan their first points of the season with a 2-1 home win over Empoli on Saturday.
Ronaldo's replacement Dybala scored in the 77th minute with a goal the Portuguese would have been proud of. After a quick exchange of passes, the Argentine twisted past Alessio Romagnoli and beat Gianluigi Donnarumma with a right foot shot.
Lionel Messi fittingly sealed Barcelona's 26th La Liga title on Saturday by coming off the bench to score the goal in a 1-0 win over Levante in front of a jubilant Nou Camp crowd, who celebrated a remarkable eighth league crown in 11 years.
Champions Bayern Munich eased past hosts Fortuna Duesseldorf 4-1 on Sunday with winger Kingsley Coman scoring twice, to go a point clear at the top of the Bundesliga.
Kylian Mbappe believes Les Bleus have what it takes to win the title in Russia if they all stick together.
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Pep Guardiola this week offered a rare insight into the pressure he feels to deliver Bayern Munich a Champions League trophy.
The Portuguese forward then fired in the penalty in the sixth minute of stoppage time.
Napoli maintained their two-point advantage at the top of Series with a 2-0 victory at Lazio on Wednesday in a game suspended due to racist chanting as Juventus beat Genoa 1-0 to break a club record for consecutive league wins in a single season.
A summary of Wednesday's matches in the UEFA Champions League.
News of all that's transpired on and off the football field
This and more from the happenings in the world of football
Coach Roberto Mancini has insisted that he never doubted his captain Mauro Icardi after the striker scored two goals in Inter Milan's 4-0 victory at Udinese in Serie A.
France midfielder Paul Pogba has rejoined Manchester United from Italian champions Juventus on a five-year contract, with the option to extend for a further year, the Premier League club said in a statement on Monday.
A summary of Wednesday's group matches in the UEFA Champions League.
